Continuous feedback-controlled heating of the vein to 85oC optimizes endothelial destruction, collagen contraction, vein wall thickening and results in vein occlusion.
Temperature controlled heating of the vein wall causes:
- Shortening and thickening of collagen fibers
- Vein lumen diameter shrinkage
- Fibrotic sealing of the vessel
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Method of Action* Fibrotic Occlusion |
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Normal caprine vein wall |
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Fibrotic occlusion of caprine |
vein lumen at 6 weeks |
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